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Science · Go deeper · Diagnosis

Check whether a biological measurement can be trusted

Use fictional controls to distinguish a sample result from a failed measurement.

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7–10 min for the lesson · application takes longer

Situation

Look closer. Ask a better question.What can you observe, and what are you only assuming?Illustrated learning characters · fictional scene

The Researcher · fictional example

The situation

A simulated enzyme assay gives a signal of 8 for a sample. A blank expected to have no reaction also gives 8; a reference expected to react gives 8. The Researcher is asked to report the sample as active.

Before you continue

What would you predict? Say it aloud or write a line on paper. Then compare your reasoning with the example.

Starting knowledge: Complete 'Tell a biological effect from a changed condition' or understand comparison groups.

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Work through Check whether a biological measurement can be trusted with a focused prompt. Your notes stay private unless you choose to paste an excerpt here.

Use fictional examples. Leave out names, contact details, passwords and private records.

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